这似乎是 Windows 游戏 (4.0) 问题.请参阅 这个 页面.您可以尝试在代码中设置图像，如下所示:

This seems to be a Windows Game (4.0) issue. See the answer on this page. You could try to set the image in your code like this:

pictureBox1.Image = Image.FromFile("path/somefile.jpg");

根据这个页面，这个问题是一个错误未修复.

According to this page, this problem is a bug that hasn't been fixed.