试试看:

var document = new XmlDocument();
document.Load("d:\\xmlfile.xml"); //or use LoadXml for a xml string 
document.ChildNodes[2]["cbc:ProfileID"].InnerXml = "Foo value";

PS: "cbc:ProfileID" 这只是一个例子.您可以使用其他属性.

PS: "cbc:ProfileID" it's just a example. You can use other properties.