list.sort ，

list.sort, sorted accept optional key parameter. key function is used to generate comparison key.

>>> sorted(lst, key=lambda x: x[1], reverse=True)
[['I', 219], ['A', 22], ['P', 14], ['V', 13], ['G', 10], ...]

>>> sorted(lst, key=lambda x: -x[1])
[['I', 219], ['A', 22], ['P', 14], ['V', 13], ['G', 10], ...]

>>> import operator
>>> sorted(lst, key=operator.itemgetter(1), reverse=True)
[['I', 219], ['A', 22], ['P', 14], ['V', 13], ['G', 10], ...]