您可以onChange处理从codebehind添加的javascript：

You could add the javascript onchange handler from codebehind:

Protected Sub GridView1_RowDataBound(ByVal sender As Object, ByVal e As System.Web.UI.WebControls.GridViewRowEventArgs)
    If e.Row.RowType = DataControlRowType.DataRow Then
        Dim hidden = DirectCast(e.Row.FindControl("rowIsChanged"), HtmlInputHidden)
        Dim txtMyDate = DirectCast(e.Row.FindControl("txtMyDate"), TextBox)
        txtMyDate.Attributes("onchange") = "DoSomeValidation(this,'" & hidden.ClientID & "');"
    End If
End Sub

C＃

protected void GridView1_RowDataBound(object sender, System.Web.UI.WebControls.GridViewRowEventArgs e)
{
    if (e.Row.RowType == DataControlRowType.DataRow) {
        var hidden = (HtmlInputHidden)e.Row.FindControl("rowIsChanged");
        var txtMyDate = (TextBox)e.Row.FindControl("txtMyDate");
        txtMyDate.Attributes("onchange") = "DoSomeValidation(this,'" + hidden.ClientID + "');";
    }
}

修改：这里是JS功能，它的工作原理设置的值，并回发后阅读：

Edit: here is the js-function, it works to set the value and read it after postback:

 <script type="text/javascript">
     function DoSomeValidation(ctrl, hiddenID) {
        var hidden = document.getElementById(hiddenID);
        if(ctrl.defaultValue != ctrl.value)
            hidden.value = "1";
     }
 </script>

EDIT2 ：添加当前文本框值之间的差值进行额外的检查，它的的设置defaultValue 。

Edit2: added an additional check for a difference between the current textbox' value and it's defaultValue.