您可以设置自动生成列为假并接受您有责任提供要设置的列列表，以避免设置DataSource或DataMember属性时自动生成列。

You can set AutoGenerateColumns to False and take responsibility in your hand to provide the list of columns you want to avoid auto generation of columns when DataSource or DataMember properties are set.

<DataGrid AutoGenerateColumns="False" ItemsSource="{Binding SourceCollection}">
  <DataGrid.Columns>
     <DataGridTextColumn Binding="{Binding Index}"/>
     <DataGridTextColumn Binding="{Binding Colour}"/>
     <DataGridTextColumn Binding="{Binding Location}"/>
     <DataGridTextColumn Binding="{Binding Srno}"/>
  </DataGrid.Columns>
</DataGrid>