1. Install Visual Studio 2005 or Visual Studio 2008 Professional or Team System editions.

Unfortunately, Express and Standard won't support develop Windows Mobile applications. It means no free IDE for Windows Mobile development available from Microsoft.

2. Install Windows Mobile 6 Professional and Standard Software Development Kits Refresh

Download and install Windows Mobile 6 SDK. 
http://www.microsoft.com/downloads/details.aspx?FamilyID=06111a3a-a651-4745-88ef-3d48091a390b&displaylang=en 
I recommend install  Professional edition.

3. Install Windows Mobile 6.5.3 Developer Tool Kit

Download and install Windows Mobile 6.5.3 DTK. 
http://www.microsoft.com/downloads/details.aspx?familyid=C0213F68-2E01-4E5C-A8B2-35E081DCF1CA&displaylang=en

    本文转自Jake Lin博客园博客，原文链接http://www.cnblogs.com/procoder/archive/2010/06/30/How_to_set_up_Window_Mobile_6_5_3_Development_Environment.html：，如需转载请自行联系原作者