Zip 他们：

dataGrid1.ItemsSource = Column1 _
                        .Zip(Column2, _
                             Function(c1, c2) New With { .Column1 = c1, .Column2 = c2 })

XAML

...
<DataGridTextColumn Binding="{Binding Column1}" />
<DataGridTextColumn Binding="{Binding Column2}" />
...