由于Access创建了.ldb文件，因此用户(模拟用户或asp用户)必须具有在目录中创建文件的权限.

The user (impersonated or the asp user) must have the permission to create files in the directory because Access creates a .ldb file.

在中描述了其他可能的原因MS知识库

更新: 您检查有效权限了吗?也许是因为显式地拒绝继承在这里起作用.

UPDATE: Did you check the effective permissions? Maybe inheritance comes into play here, because of an explicit deny.