从它的声音来看，您希望在构建文件路径时使用 Application.StartupPath，因此类似于以下内容；

From the sounds of it you want to be using Application.StartupPath when constructing your file path so something along the lines of;

System.IO.Path.Combine(Application.StartupPath, "myfile.txt");

如果您想将当前目录设置为正确的目录(尽管我个人建议使用 Application.StartupPath 而不是相信当前目录是正确的)，您可以这样做；>

If you want to set the current directory to the right directory (although personally I would recommend using the Application.StartupPath rather than trust the current directory will be right) you can do this;

System.IO.Directory.SetCurrentDirectory(Application.StartupPath);

至于原因，我曾遇到过这样的情况:打开文件打开对话框，然后导航到另一个位置，然后该位置成为当前目录.

As for why, I've had occasions where you do something like open a file open dialog then navigate to another location, which then becomes the current directory.