如果您要删除包含任何空白（制表符，空格）线，请尝试：

If you want to remove lines containing any whitespace (tabs, spaces), try:

string fix = Regex.Replace(original, @"^\s*$\n", string.Empty, RegexOptions.Multiline);

Edit（对于@Will）：修剪后的新行最简单的办法是使用的 TrimEnd 上生成的字符串，例如：

Edit (for @Will): The simplest solution to trim trailing newlines would be to use TrimEnd on the resulting string, e.g.:

string fix =
    Regex.Replace(original, @"^\s*$\n", string.Empty, RegexOptions.Multiline)
         .TrimEnd();