您正在尝试发送到广播地址.这是不允许的，请参阅 sendto(2) 的手册页:

You are trying to send to a broadcast address. It is not allowed, see manpage for sendto(2):

EACCES(对于 UDP 套接字)尝试发送到网络/广播地址，就好像它是单播地址一样.

EACCES (For UDP sockets) An attempt was made to send to a network/broadcast address as though it was a unicast address.

设置 SO_BROADCAST 选项，如果您实际上是要发送到广播地址:

Set the SO_BROADCAST option, if you actually mean to send to a broadcast address:

s.setsockopt(socket.SOL_SOCKET, socket.SO_BROADCAST, 1)